Metformin may work via the gut, not the liver
Hacker NewsMay 8, 2026
metformindiabetesgut-healthmedicationresearch
Recent research suggests that the diabetes medication metformin may exert its effects primarily through the gut rather than the liver, challenging long-held beliefs about its mechanism of action. This finding could have significant implications for the development of new treatments for diabetes and related metabolic disorders, as it opens up new avenues for therapeutic exploration.